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What if one enzyme could protect your arteries and your brain? Most people think natokinase is just about heart health—but the science now tells a much bigger story. In this episode of MedHeads, you uncover cutting-edge research revealing how natokinase, a powerful fibrinolytic enzyme, may help protect the brain from ischemic stroke, reduce neuroinflammation, and even interfere with the toxic protein buildup seen in Alzheimer’s disease. Here’s the problem: 🧠 87% of strokes are caused by blood clots, and vascular dysfunction is a major driver of cognitive decline and dementia. Yet most brain-health conversations ignore blood flow entirely. That’s where natokinase changes everything. You’ll discover: How natokinase improves cerebral blood flow and reduces infarct size after stroke Why animal studies show it can break down amyloid-beta fibrils, the core of Alzheimer’s plaques How it influences BDNF, inflammation, oxidative stress, and the blood–brain barrier Why vascular health may be the missing link in long-term cognitive protection What human pilot studies suggest—and where the science still urges caution This is not hype. It’s a sober, evidence-based look at preclinical and emerging human research that could reshape how we think about brain aging. If you care about: brain health, stroke prevention, Alzheimer’s research, cognitive longevity, inflammation, blood flow, and natural enzymes—this episode is essential viewing. 👉 Watch now, share with someone thinking about brain health, and subscribe to MedHeads for science-driven insights you won’t hear anywhere else. Timestamps: 00:00 – The enzyme that clears clots and may protect the brain 00:33 – Why ischemic stroke dominates brain injury 01:10 – Natokinase and neuroprotection in stroke models 01:46 – The Alzheimer’s connection: amyloid plaques explained 02:11 – Natokinase breaking down amyloid-beta fibrils 02:59 – BDNF, inflammation, and neuronal survival 03:22 – Can natokinase cross the blood–brain barrier? 04:35 – What human studies actually show 05:05 – Stroke, dementia risk, and vascular aging 05:38 – Final takeaways for long-term brain health