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In this episode, pioneering neurologist Dr. Richard Isaacson discusses the future of Alzheimer's prevention, highlighting his cutting-edge research and the crucial role of personalized medicine. Dr. Isaacson explains how researchers can now use genetic data and risk factors to design individualized care plans, benefiting high-risk individuals earlier than in the past. He takes listeners through the ways that genetic predispositions inform prevention strategies and outlines evidence-based interventions that are being used to develop a robust preventive framework. The conversation covers emerging technologies like digital health tracking, cognitive monitoring, and non-invasive diagnostic testing, which are bringing us into a new era of Alzheimer's prevention. Note: This lecture was recorded in April 2022. Learn more about Dr. Richard Isaacson’s work: https://www.atria.org/doctors/dr-rich... Learn more about Dr. David Dodick: https://www.atria.org/doctors/dr-davi... Time stamps: 00:00:19: Intro 00:02:44: Dr. Richard Isaacson 00:10:08: Alzheimer’s as a disease of middle age 00:11:03: Dr. Isaacson’s approach to Alzheimer’s prevention 00:14:30: Modifiable risk factors for Alzheimer's prevention 00:18:48: Using comparative effectiveness research to find real-world clinical evidence 00:19:50: Implementing precision medicine to individualize care 00:21:24: The ABCs of Alzheimer's prevention management for creating bespoke treatment plans 00:26:35: Nutritional interventions for Alzheimer’s disease 00:31:34: Importance of diet in healthy brain function 00:34:42: Addressing stress and mental health in Alzheimer's prevention 00:38:00: Personalized Alzheimer's prevention methods in Dr. Isaacon’s research 00:43:38: Findings and the surprise of improved cognitive function among people with Mild Cognitive Impairment 00:47:00: The real-world effects of this study on clinical practice 00:51:13: The role of genetics in Alzheimer’s research 00:53:00: Case study of an Apo-E 4 patient 00:58:22: Importance of oral health in Alzheimer’s prevention 01:00:35: Public education on Alzheimer’s disease prevention 01:01:30: Alzheimer's prevention support group 01:04:03: Focus on taking control of prevention — About: Atria’s Vanguard Symposia is a lecture series where some of the world’s most compelling researchers translate leading-edge science into medicine. In each episode, top experts share breakthrough science about preventive health care, dive deep into headline-grabbing topics, and take you beyond the buzzwords to explain the latest in longevity science. Our show will arm you with practical information and the tools of discernment to cut through the hype and understand what matters most. Atria Health and Research Institute aims to accelerate a global shift from reactive sick care to proactive, preventive health care. We work at the forefront of science and technology and we believe a collaborative approach to modern medicine can extend healthy life for all. Learn more: https://www.atria.org/ Subscribe to Atria’s Vanguard Symposia on: Apple Podcasts: https://bit.ly/AtriaVanguardApplePodc... Spotify: https://bit.ly/AtriaVanguardSpotify Sign up for our newsletter: https://bit.ly/Atria-Newsletter The information contained in this podcast is for general informational and educational purposes only and does not constitute or serve as a substitute for professional medical advice, treatment, or diagnosis. Always consult the advice of your personal health care provider when seeking medical advice for any condition you may have, and never delay treatment or disregard advice from a professional health care provider based on something you have seen or heard in this content. No part of this podcast can be reproduced, redistributed, published, copied or duplicated in any form without the prior written permission of Atria.