The Science of Pausing and Reversing Aging | Laura Deming and Jacob Kimmel скачать в хорошем качестве

The Science of Pausing and Reversing Aging | Laura Deming and Jacob Kimmel

Two founders are racing to solve aging from completely different directions, one by freezing organs to pause time, the other by reprogramming cells to reverse it. On this episode of Builders, hosts Josh Coyne and Leigh Marie Braswell sit down with Laura Deming (Until) and Jacob Kimmel (NewLimit) to get into the real science behind cryo-preservation and epigenetic reprogramming and how AI is changing the speed at which both are moving. "If you could just pause time when you had a terminal illness and turn it back on when the cure was there, that'd be amazing." - Laura Deming (Until) "I made these old cells look young and it worked every time. I couldn't get the idea out of my head." - Jacob Kimmel (NewLimit) Highlights from the discussion: How Until is scaling frozen organ technology from rat kidneys to human-scale organs. Why NewLimit's first anti-aging medicine could enter human trials soon. The role AI is playing in doubling the rate of longevity drug discovery. Guests: Laura Deming, CEO at Until, and Jacob Kimmel, Co-founder & President at NewLimit Connect with us here: Jacob Kimmel: X: https://x.com/jacobkimmel?lang=en LinkedIn:   / jacob-kimmel   Laura Deming: X: https://x.com/LauraDeming LinkedIn:   / laura-deming-b255362a   Leigh Marie Braswell: X: https://x.com/LM_Braswell LinkedIn:   / leigh-marie-braswell   Josh Coyne: X: @josh_coyne LinkedIn:   / joshuacoyne   ​Learn more about Kleiner Perkins: https://www.kleinerperkins.com/ 00:00 Trailer 01:03 Introduction 06:51 How It Works: Epigenetics + Vitrification 11:13 Roadmaps, Hiring, and Scaling Science 23:57 Virtual Cell Roadmap (Why Experiments Don’t Scale) 31:16 Reversing Eroom’s Law: AI Cutting Drug Costs + Faster Trials 35:46 What’s Next: Energy, Gene Editing, Sleep + Longevity Habits