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This is a shortened version from the fourth lecture in the module ‘Born to Run-The Science of Human Endurance’. It discusses a number of different models of fatigue (in the context of endurance exercise), including the peripheral and central governor models of fatigue. The issue with peripheral models of fatigue (where a slowing of pace is caused by, for example, your muscles not being strong enough or your heart not pumping fast enough) is that it cannot explain the “end spurt” that we so often see in both elite and recreational running; with the right incentive, athletes are able to speed up. Only the brain can respond to abstract incentives (like breaking four hours for an arbitrary distance like 26.2 miles). This idea, that it is actually the brain that determines performance in a process of “anticipatory regulation”, was first proposed in 1998 by Professor Tim Noakes. #endurancerunning #learnonyoutube #crashcourse #marathonrunning #sportsscience #physiotherapy #exercisephysiology Reference list: https://doi.org/10.1123/ijspp.1.3.233 https://doi.org/10.1249/mss.0b013e318... https://doi.org/10.1249/00005768-1982... https://doi.org/10.1287/mnsc.2015.2417 https://doi.org/10.2165/00007256-2007...