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Subscribe to our channel: / @optispan Get Our Newsletter (It's Free): https://www.optispan.life/ The longevity supplement industry is full of hype, marketing claims, and questionable science. In this episode, Matt breaks down 13 popular supplements through an evidence-based lens. Subscribe for more evidence-based longevity content. This video was produced by One Billion Media, an agency that specializes in YouTube virality for health brands and experts. Learn more about their work here: https://onebillionmedia.com/ 0:00 - Introduction: 13 Supplements Ranked 1:41 - How the Tier List Works (Strong, Good, Promising, Overhyped, Avoid) 2:27 - Fucoidin 8:04 - Fisetin 8:54 - Lithium Orotate 12:34 - Resveratrol 13:24 - Creatine 14:58 - CoQ10 15:53 - SS Peptides (SS-31/Elamipretide) 24:09 - Proprietary "Anti-Aging" Blends 24:55 - NAD+ Precursors 27:17 - Omega-3 28:47 - Vitamin D 29:24 - Fatty 15 (Pentadecanoic Acid) 31:01 - Urolithin A 32:31 - Final Rankings: All 13 Supplements Ranked 1-13 34:41 - Closing Thoughts DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find us: Twitter: https://x.com/Optispan_Inc Twitter: / mkaeberlein Linkedin: / optispan Instagram: / optispan_ TikTok: / optispan https://www.optispan.life/ Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it. On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!