New Clues to Parkinson's Disease From An Unlikely Source скачать в хорошем качестве

New Clues to Parkinson's Disease From An Unlikely Source

May 21, 2008 Dr. Susan Lindquist Whitehead Institute for Biomedical Research/Massachusetts Institute of Technology What do "mad cows," people with neurodegenerative diseases, and yeast cells growing profusely on a deadly antibiotic have in common? They are all experiencing the consequences of misfolded proteins. These proteins must fold into just the right shape to do their jobs properly. Dr. Lindquist explaines what happens when proteins misfold. In humans, the consequences of protein misfolding can be deadly, leading to devastating neurodegenerative diseases such as Parkinson's and Huntington's disease. Lindquist has been studying yeast to screen for genes that may improve the ill effects caused by misfolding proteins in Parkinson's disease. The genetic pathways she is identifying represent promising targets for the development of new drugs that may lead to innovative treatments for diseases such as Parkinson's.