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Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this reproductive physiology lecture, Professor Zach Murphy explains ovulation, the central event of the female menstrual cycle. This session focuses on the hormonal regulation, follicular dynamics, and clinical relevance of the ovulatory process—crucial knowledge for understanding fertility, contraception, and menstrual physiology. We review the hypothalamic-pituitary-ovarian (HPO) axis, where GnRH from the hypothalamus stimulates the anterior pituitary to release FSH and LH. These gonadotropins act on the ovarian follicles, promoting follicular growth and estradiol production. As estrogen levels rise, a unique positive feedback loop is triggered, leading to the LH surge—the key hormonal signal that induces ovulation. The lecture then walks through the structural changes in the dominant follicle, including oocyte maturation, follicular rupture, and release of the secondary oocyte into the peritoneal cavity. You’ll also learn about the formation of the corpus luteum and its role in progesterone production during the luteal phase. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media / ninjanerdlectures / ninjanerdlectures / ninjanerdlectures https://x.com/ninjanerdsci/ / ninja-nerd 💬 Join Our Community Discord: / discord #ninjanerd #Ovulation #FemaleReproductiveCycle