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Diabetic Ketoacidosis (DKA) Explained | Biochemistry, Pathophysiology & Management | Dr. Priyadarshini V A clear, clinically focused session on Diabetic Ketoacidosis (DKA) by Dr. Priyadarshini V, covering the biochemistry of ketone body production, core pathophysiology, and emergency management principles in a simple, logical flow. This talk connects basic science with bedside decision-making, explaining how insulin deficiency and excess counter-regulatory hormones lead to lipolysis, ketogenesis, electrolyte imbalance, and high anion gap metabolic acidosis. Ideal for emergency physicians, residents, medical students, and critical care teams—building strong conceptual clarity for both exams and real-life emergencies. Key Topics Covered: Definition and diagnostic triad of DKA Role of insulin deficiency & counter-regulatory hormones Lipolysis and free fatty acid metabolism Beta-oxidation and acetyl-CoA overload Ketone body formation: acetoacetate, beta-hydroxybutyrate & acetone High anion gap metabolic acidosis explained Anion gap calculation and clinical relevance Potassium shifts and electrolyte abnormalities Kussmaul respiration as compensatory mechanism Ketone detection: urine vs serum beta-hydroxybutyrate Core management principles: fluids, insulin & potassium Life-threatening complications of untreated DKA 🔔 Subscribe to SEMI India for more high-yield Emergency Medicine lectures and concept-driven clinical education. ⚠️ Disclaimer: This video is for educational purposes only. Clinical decisions must follow institutional protocols, current guidelines, and individual patient context.