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"Keynote Title: ""Towards Synergistic Human–Machine Interaction in Assistive and Rehabilitation Robotics: Multimodal Interfaces, Sensory Feedback, and Future Perspectives"" Speaker Biography Loredana Zollo received MS in Electronic Engineering in 2000 from Università degli Studi di Napoli “Federico II”, and the PhD in Bioengineering in 2004 from Scuola Superiore Sant’Anna di Pisa. She is Full Professor of Bioengineering, Dean of Engineering and Director of the PhD Program in Bioengineering, Applied Sciences and Intelligent Systems at Università Campus Bio-Medico di Roma. In the same university she is the director of the CREO Lab – Laboratory of Advanced Robotics and Human-Centred Technologies. She currently is President of the National Institute for Robotics and Intelligent Machines (I-RIM), a non-profit association established with the mission to promote the development and application of robotic technologies and intelligent systems, with the overarching aim of enhancing societal well-being, improving quality of life, and supporting the sustainability of production systems. Loredana Zollo’s research interests are mainly in the fields of biomedical robotics, biorobotics and bionics, human-machine interfaces, collaborative robotics, robotics for agritech. She has been involved in 40+ EU-funded and national projects in her application fields. She has authored/co-authored 250+ scientific publications and 6 patents. Abstract Recent advancements in assistive and rehabilitation robotics have demonstrated the growing potential of current technologies to restore communication with the nervous system along both afferent and efferent pathways, primarily through the development of closed-loop human–robot interfaces. This talk will explore the synergistic interaction between users and robotic systems, highlighting how such integration enables motor recovery and functional substitution in individuals with motor impairments or limb loss. Starting from a critical overview of the state of the art, the presentation will delve into recent advances in multimodal interfaces and sensory feedback mechanisms, including haptic and proprioceptive feedback, integrated into rehabilitation and assistive robots. Finally, the discussion will open toward future perspectives, highlighting key challenges and research directions in the field, including long-term adaptability, user-specific customization, and the convergence of bioengineering, AI, and robotics to shape the next generation of assistive and rehabilitative technologies.