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Pathologist's Perspective on Focal Therapy

M. Scott Lucia, MD, Professor and Vice Chair of the Department of Pathology and Director of Anatomic Pathology of the Prostate Diagnostic Laboratory at the University of Colorado Anschutz Medical Campus (CAMC) School of Medicine reviews study data to help physicians decide which biopsy route is best when selecting patients for focal therapy. Using results from the SEER, PROMIS, and PRECISION studies, among others, he argues that TRUS biopsies are insufficient and miss too many high-grade tumors, while TTMP plus mpMRI guided biopsy appears to provide the most accurate results.