Serotonin: Supporting Survival in Plants, Animals, & Us (8 Sources: 2001-24) скачать в хорошем качестве

Serotonin: Supporting Survival in Plants, Animals, & Us (8 Sources: 2001-24)

I. The Ancient Origins Of Serotonin Serotonin functions in behaviors central to human life It appeared evolutionarily before neurons existed Its history begins 3 billion years ago with tryptophan Early life used tryptophan to capture light energy It helps regulate homeostasis in simple organisms II. Serotonin In The Plant Kingdom Plants synthesize much higher levels than mammals It acts as an antioxidant against reactive oxygen It regulates root growth and leaf positioning Tryptophan is vital for photosynthesis energy Serotonin helps move plant organs toward light III. The Animal Evolutionary Shift Animals lost the ability to synthesize tryptophan We must obtain this essential amino acid from diet Animals developed mechanisms to conserve tryptophan Multiple receptors evolved to maximize efficiency It regulates social dominance in higher animals IV. The Light & Mood Connection Tryptophan absorbs light due to its indole ring Sunlight exposure increases brain serotonin turnover Seasonal Affective Disorder links to low light Light therapy mimics these evolutionary benefits Blue light is most effective for this system V. Brain & Behavior Regulation Regulates mood, sleep, and aggression Low levels linked to depression and suicide Acts as a trophic factor for brain cells Loss of serotonin leads to loss of synapses Chronic stress diverts tryptophan away VI. Roles In Gut & Circulation Most serotonin resides in the gut mucosa It regulates intestinal motility and secretions Platelets store it to help with blood clotting It constricts blood vessels during injury Dysregulation is linked to IBS and migraines VII. Additional Resource Support See NourishED RFI's NotebookLM Resource Support Page. https://notebooklm.google.com/noteboo... VIII. Sources 1. Azmitia. (2001). Modern Views on an Ancient Chemical: Serotonin Effects on Cell Proliferation, Maturation, & Apoptosis. Brain Res Bull, 56(5), 413-424. 2. Azmitia. (2009). Evolution of Serotonin: Sunlight to Suicide. In Handbook of Behavioral Neuroscience (Vol. 31, pp. 3-22). Elsevier. 3. Russo et al. (2009). Tryptophan as an Evolutionarily Conserved Signal to Brain Serotonin: Molecular Evidence & Psychiatric Implications. World J Biol Psychiatry, 10(4), 258-268. 4. Pelagio-Flores et al. (2011). Serotonin, A Tryptophan-Derived Signal Conserved in Plants & Animals, Regulates Root System Architecture Probably Acting as a Natural Auxin Inhibitor in Arabidopsis Thaliana. Plant Cell Physiol, 52(3), 490-508. 5. Erland & Saxena. (2017). Beyond a Neurotransmitter: the Role of Serotonin in Plants. Neurotransmitter, 4(5), 1-12. 6. Höglund, Øverli, & Winberg. (2019). Tryptophan Metabolic Pathways & Brain Serotonergic Activity: A Comparative Review. Front Endocrinol (Lausanne), 10, 158. 7. Negri et al. (2021). The Case of Tryptamine & Serotonin in Plants: A Mysterious Precursor for an Illustrious Metabolite. Journal of Experimental Botany, 72(15), 5336–5355. 8. Tanveer et al. (2024). Unlocking the Mysteries: Serotonin Receptor Networks Explored. In Serotonin-Neurotransmitter & Hormone of Brain, Bowels & Blood. IntechOpen. #serotonin #neuroscience #evolution #biology #brainhealth #tryptophan #mentalhealth #scienceeducation #photobiology #neurotransmitters #tryptamine #auxin #botany #plantbiology ‪@KnowTime‬ ‪@NIMHgov‬ ‪@NIHgov‬ ‪@NIHVideoCast‬ ‪@BBRFoundation‬ ‪@hopefordepressionresearchf8989‬ ‪@psychedelicsupport‬ ‪@naropaallianceforpsychedel7015‬ ‪@mensmentalhealthinstitute‬ ‪@AuthenticMentalHealth‬ ‪@kcbotanystudycentre‬ ‪@BotanyPhDDiariesGR‬ ‪@PlantEnergyBiology‬ ‪@idealplantbiology4883‬ ‪@evolution‬ ‪@evolutionshort.4790‬ ‪@EvolutionPrimitiveTime‬ ‪@YourPlantBasedEvolution-2025‬ ‪@TheStonedApes‬ ‪@StonedApeTheories‬ ‪@StonedApe710‬ ‪@Serotonin99‬