CO₂-to-Chemicals Biotechnology Using Acetogenic Fermentation-Yutaka Nakashimada скачать в хорошем качестве

CO₂-to-Chemicals Biotechnology Using Acetogenic Fermentation-Yutaka Nakashimada

Professor Yutaka Nakashimada Unit of Biotechnology Division of Biological and Life Sciences Graduate School of Integrated Sciences for Life Hiroshima University Abstract The Government of Japan has recently declared a target of reducing greenhouse gas emissions by 46% by 2030 compared to 2013 levels, and achieving net-zero emissions by 2050. To meet these ambitious goals, Japan has established the Green Innovation Fund, which aims to develop a world-class energy and material utilization system that balances economic efficiency with environmental performance. In the bioindustry sector, the key technology for carbon recycling is the development of production processes that combine the high selectivity of conventional target-compound synthesis with high economic efficiency, achieved through energy-saving process design. To realize such technologies, we are advancing research and development on gas fermentation. Anaerobic acetogenic bacteria generally produce acetic acid from syngas or H₂/CO₂. We are currently conducting a pilot-scale demonstration on Osaki-Kamijima Island (Hiroshima Prefecture), where we produce acetate from H₂/CO₂ for CO₂ recycling using a mesophilic acetogen. Furthermore, we are developing a thermophilic syngas-fermentation process to produce low-boiling bulk chemicals through genetic engineering of the thermophilic acetogen Moorella thermoacetica. Using this platform technology, we have successfully constructed genetically modified strains capable of producing C₂ to C₄ compounds from sugars, syngas, and H₂/CO₂. In this presentation, I will introduce our recent progress in biotechnology aimed at contributing to carbon recycling. Disclaimer: This project was supported by the Department of Science, Innovation and Technology’s International Science Partnerships Fund (ISPF) via the Royal Academy of Engineering under the Frontiers Champions scheme.